This experiment was conducted to evaluate the effects of adding DL-selenomethionine to the sow diet on the pancreas selenium content, antioxidant capability, digestive enzyme activities and GSH-Px mRNA expression in the offspring. A total of 12 healthy sows (Landrace×Yorkshire, with the same parity in late gestating period) were allocated into 2 groups (sodium selenite group and DL-selenomethionine group) with 6 replicates each and 1 sow in each replicate. Sodium selenite group and DL-selenomethionine group were fed with basal diet (Se 0.04 mg/kg, measured value) supplemented with 0.3 mg/kg sodium selenite and DL-selenomethionine, respectively. The total test period lasted for 60 days, 32 days of gestation and 28 days of lactation. The results showed that compared with sodium selenite group, the pancreas selenium content of suckling pigs in DL-selenomethionin group was increased by 54.29% (P<0.01), T-AOC, GSH-Px and SOD activity, and GSH content were increased by 112.52% (P<0.01), 22.84% (P<0.01), 24.60% (P<0.01) and 131.14% (P<0.01), respectively, MDA content was decreased by 25.55% (P<0.01); amylase, trypsin and lipase activities were increased by 50.81% (P<0.01), 17.61% (P<0.05) and 14.87% (P<0.05), respectively; expression of GSH-Px mRNA was increased by 28.13% (P<0.01). These results suggest that DL-selenomethionine can enhance the pancreas selenium content, antioxidant capacity, and digestive enzyme activity, and increase the GSH-Px mRNA expression in the suckling pigs.［Chinese Journal of Animal Nutrition, 2010，22（5）:1361-1366］