The differences in metabolizable energy and true amino acid digestibility of 12 soybean meal samples using adult ducks as experimental animals were investigated to study the variation in the bioavailability of macronutrients of soybean meals. A completely randomized design was used and each sample of soybean meal was a treatment with 4 replicates each and 12 ducks in each replicate. Sibbald’s emptyingforcefeeding method was used to determine the metablizable energy and true amino acid digestibility of soybean meals. The results showed that the metabolizable energy of sample 3 was significantly higher than that of samples 4, 8, 9, 10, 11, 12 (P<0.05) and sample 7 was significantly higher than that of samples 8, 11, 12 (P<0.05). The true digestibilities of total amino acids of sample 7, 8, 9 were significantly higher than those of samples 1, 2, 3, 4, 5, 12 (P<0.05). There was no significant difference in the true digestibilities of 17 amino acids among samples 6, 7, 8, 9, and between samples 2, 3 and samples 1, 4 (P>0.05). There was significant difference in the true digestibility of some amino acids among other samples (P<0.05). In conclusion, according to the relationship between the chemical compositions and metabolizable energy, true amino acid digestibility of 12 soybean meals, the difference in metabolizable energy of soybean meals was probably related to the percentage of soybean hull, however, the difference in true amino acid digestibility was related to the origin of soybean and production process.