This experiment was conducted to study the effects of selenium yeast on the immune and anti-oxidation indices of geese. Ninety-six 1-day-old geese with an average body weight of （96.15±6.15） g were randomly divided into 4 groups with 3 replicates of 8 geese in each replicate (48 males and 48 females). Geese in 4 groups were fed diets with 0, 0.10, 0.30 or 0.50 mg/kg selenium (1 kg of yeast selenium provided 1 000 mg selenium), respectively. The experiment lasted for 9 weeks. The results showed that compared with control group, (1) immune indices: the immune organ indices increased significantly in 0.3 mg/kg group (P<0.05), the lymphocyte transformation rate (LTR) was increased significantly by adding 0.1～0.5 mg/kg selenium (P<0.05), the antibody titer (6 week) increased significantly in 0.3 mg/kg group (P<0.05); (2) anti-oxidation indices: for the diet with 0.1 mg/kg selenium, the activities of GSH-Px (3, 9 week), T-SOD (6 week) and T-AOC (3, 6 week) in serum and GSH-Px (3, 6, 9 week), T-SOD (3, 9 week) and T-AOC (3 week) in liver increased significantly (P<0.05); for the diet with 0.3 mg/kg selenium, the activities of GSH-Px (3, 6, 9 week), T-SOD (6 week) and T-AOC (3, 6, 9 week) in serum and GSH-Px (3, 6, 9 week), T-SOD (3, 9 week) and T-AOC (6 week) in liver increased significantly (P<0.05); for the diet with 0.5 mg/kg selenium, the activities of GSH-Px (3 week), T-SOD (3 week), T-AOC (3, 6 week) in serum and GSH-Px (3, 6, 9 week) and T-SOD (3, 9 week) in liver increased significantly (P<0.05). The MDA in serum and liver were reduced significantly by adding 0.1～0.5 mg/kg selenium (P<0.05). It was concluded that adding yeast selenium to the diet could improve the immune and anti-oxidation ability of geese, and the optimal supplemental level of selenium was 0.3 mg/kg.