This experiment was conducted to investigate the effects of dietary supplementation with copper (Cu), iron (Fe) and zinc (Zn) on contents of lead (Pb) and cadmium (Cd) in tissues and blood of beef cattles. Twenty beef cattles aged 12 months were randomly divided into 2 groups with 10 cattles in each group. Cattles were fed a basal concentrate (control group) and the basal concentrate supplemented with 20 mg Cu, 200 mg Fe and Zn 200 mg (experimental group), respectively. Roughage was fed ad libitum. The experiment lasted for 150 d. Feed intake of cattles were calculated by group per day; body weight was recorded and blood sample was collected every 30 d, at the end of the experiment, all cattles were slaughtered to collect samples of kidney, liver, heart, pancreas, spleen, rumen, large intestine and dorsal muscles, and the contents of Pb and Zn in tissues and blood were determined. The results showed as follows: supplementation of Cu, Fe and Zn in concentrate significantly increased average daily gain by 12.50% (P<0.01), but significantly decreased feed to gain by 15.68% (P<0.01); there was a significant increase in Pb content in pancreas and rumen (P<0.01), and a significant decrease in that in spleen and blood (P<0.05), but Pb content in other tissues was not changed significantly (P>0.05), and Pb mainly accumulated in the rumen; Cd contents in kidney, liver, spleen, rumen and large intestine were all significantly increased (P<0.01), but Cd content in heart was significantly decreased (P<0.01), and Cd mainly accumulated in the kidney. The results indicate that dietary supplementation with Cu, Fe and Zn can improve growth performance of beef cattles, but can not effectively reduce the accumulation of Pb and Cd in tissues and muscles.
CAI Qiu
,
ZHANG Mingzhong
,
LIU Kangshu
,
ZHU Ming
,
SHU Danqiu
,
WANG Xingning
,
LU Cunren
,
LUAN Junming
. Dietary Supplementation with Copper, Iron and Zinc Affects Contents of Lead and Cadmium in Tissues and Blood of Beef Cattles[J]. Chinese Journal of Animal Nutrition, 2012
, 24(3)
: 571
-576
.
DOI: 10.3969/j.issn.1006-267x.2012.03.026
[1] MOHAN J,MOUDGAL R P,PANDA J N.Effects of cadmium salt on phosphomonoesterases activity and fertilizing ability of fowl spermatozoa[J].Indian Experiment Biology,1992,30:241-243.
[2] ELSENHANS B,KOLB K,SCHUMANN K,et al.The longitudinal distribution of cadmium, zinc, copper, iron, and metallothionein in the small intestinal mucosa of rats after administration of cadmium chloride[J].Biology Trace Element Research,1994,41:31-46.
[3] CROWE A,MORGAN E H.Effect of dietary cadmium on iron metabolism in growing rats[J].Toxicology Application Pharmacology,1997,145:136-146.
[4] 杨占军.铅对小鼠神经行为的影响及锌的拮抗效应[J].工业卫生与职业病,2008,34(1):18-20.
[5] 黄益宗.镉与磷、锌、铁、钙等元素的交互作用及其生态效应[J].生态学杂志,2004,23(2):92-97
[6] 汪会玲,孟晶,徐海滨,等.饲料中硒锌水平对铅暴露大鼠脑和肾病理变化的影响[J].卫生研究,2006,35(4):507-508.
[7] 蒋洪茂.无公害肉牛安全手册[M].北京:中国农业出版社,2008:129-130.
[8] 陈绍国,方亮,刘陶发,等.适合贵州省农村的肉牛日粮及矿物质添加剂研究[J].中国饲料,1997,20:13-15.
[9] 杨正德.不同铜添加水平对肉牛铜代谢及其肥育性能的影响[J].中国畜牧杂志,2000,36(3):14-16.
[10] 姜惠敏,韩国家,历保秋.锌和硒对镉诱导大鼠体内脂质过氧化拮抗研究[J].山东医科大学学报,1994,32(2):127-129.
[11] DEGUEY L W,WAHLSTROM R C,EMERICK R J.Studies of high level copper supplementation to rations for growing swine[J].Journal of Animal Science,1971,33(1):52-57.
[12] 张微,贾志海,卢德勋,等.日粮铜水平对绒山羊瘤胃代谢的影响[J].中国饲料,2006(3):10-13.
[13] 朱秀高,薄智勇,胡颖,等.近年来高铜饲料的营养与毒性研究进展[J].粮食与饲料工业,2009(12):31-33.
[14] 陆兴熠,孟林,钟进义.环境因素和血钙、铁、锌对儿童血铅水平的影响及干预效果分析[J].中国地方病学杂志,2008,27(4):458-460.
[15] 朱圣陶,傅春玲,江伟威,等.某些营养素对短期染毒铅镉汞在小鼠体内分布的影响[J].工业卫生与职业病,2005,31(5):305-309.
[16] WANG H L,TAO S.Application of biomarkers in aquatic environmental research[J].China Environmental Science,1999,19(5):421-426.
[17] 周新文,朱国念,JILISA M,等.重金属离子Cu Zn Cd的相互作用对Pb在鲫鱼组织中积累的影响[J].农业环境保护,2002,21(1):23-25,36.
[18] 黄益宗.镉与磷、锌、铁、钙等元素的交互作用及其生态学效应[J].生态学杂志,2004,23(2):92-97.
[19] 汪再娟,金锋,施鹭明,等.人体中钙、锌、硒、铁等元素对环境镉污染影响的研究[J].中国公共卫生,1999,15(4):339-340.
[20] RAMBECK W A,BREHM H W,KOLLMER W E.The effect of increased copper supplements in feed on the development of cadmium residues in swine[J].Zeitschrift fur Emahrungswissenschaft,1991,30:298-306.
[21] ROTHE S,GROPP J,WEISER H,et al.The effect of vitamin C and zinc on the copper-induced increased of cadmium residues in swine[J].Zeitschrift fur Emahrungswissenschaft,1994,33:61-67.
