Effects of Chitosan Oligosaccharide on Growth Performance, Meat Quality, Antioxidant Capacity and Immune Function of Growing-Finishing Pigs

  • SU Weifa ,
  • ZHOU Hongbin ,
  • JIANG Denghu ,
  • LIU Xin ,
  • WANG Yizhe ,
  • WANG Xinxia ,
  • LU Zeqing
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  • 1. Key Laboratory of Animal Nutrition and Feed Science of Zhejiang Province, Key Laboratory of Animal Nutrition and Feed Science in Eastern China, Ministry of Agriculture, National Engineering Laboratory of Biological Feed Safety and Pollution Prevention and Control, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China;
    2. Dalian Chengsan Animal Husbandry Co., Ltd., Dalian 116000, China

Received date: 2020-10-22

  Online published: 2021-05-14

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Abstract

This study was conducted to investigate the effects of chitosan oligosaccharide (COS) on growth performance, meat quality, antioxidant capacity and immune function of growing-finishing pigs. Two hundred and twenty-five Duroc×Landrace×Yorkshire growing pigs with similar body weight of (37.00±1.55) kg were randomly divided into 3 groups with 3 replicates per group and 25 pigs per replicate. Pigs in the control group were fed a basal diet, those in the COS group were fed the basal diet supplemented with 30 mg/kg COS, and those in the low energy and low protein+COS group were fed a low level of dietary energy and protein diet (adjusting the feed formulation to make the basal diet minus 1% crude protein and 0.21 MJ/kg digestible energy) supplemented with 30 mg/kg COS. The trial lasted for 98 days. The results showed as follows:1) compared with the control group, the ratio of feed to gain of growing-finishing pigs in the COS group was significantly reduced (P<0.05). 2) Compared with the control group, the contents of inosinic acid and some umami amino acids (glutamate, phenylalanine and alanine) in longissimus dorsi of growing-finishing pigs in the COS group were significantly increased (P<0.05). 3) Compared with the control group, the serum total antioxidant capacity of growing-finishing pigs in the COS group was significantly increased (P<0.05), and the serum malondialdehyde content was significantly decreased (P<0.05). Meanwhile, the mRNA relative expression levels of antioxidant genes, including glutathione peroxidase 1 (GPx1), glutathione peroxidase 4 (GPx4) and p53 in liver of growing-finishing pigs in the COS group were significantly increased (P<0.05). 4) Compared with the control group, serum contents of immunoglobulin G and immunoglobulin M of growing-finishing pigs in the COS group were significantly increased (P<0.05), and the serum immunoglobulin M content of growing-finishing pigs in the low energy and low protein+COS group was also significantly increased (P<0.05). Meanwhile, the serum complement 4 content of growing-finishing pigs in the COS group and the low energy and low protein+COS group was significantly increased (P<0.05). 5) Compared with the control group, the villus height to crypt depth ratio in duodenum of growing-finishing pigs in the COS group was significantly increased (P<0.05). In conclusion, the supplementation of 30 mg/kg COS in the basal diet can improve the growth performance and meat quality in a certain extent of growing-finishing pigs by enhancing the immune function, the antioxidant capacity and the intestinal mucosa morphology.

Cite this article

SU Weifa , ZHOU Hongbin , JIANG Denghu , LIU Xin , WANG Yizhe , WANG Xinxia , LU Zeqing . Effects of Chitosan Oligosaccharide on Growth Performance, Meat Quality, Antioxidant Capacity and Immune Function of Growing-Finishing Pigs[J]. Chinese Journal of Animal Nutrition, 2021 , 33(5) : 2555 -2567 . DOI: 10.3969/j.issn.1006-267x.2021.05.016

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